Research at Banbury Cross Health Centre

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About Research at Banbury Cross Health Centre

Most of the practices which merged to form Banbury Cross Health Centre have been involved in supporting primary care research for several years.

We believe it is important to participate in research projects so that we can help to develop new and more effective ways of diagnosing and treating diseases. We are pleased to give our patients the opportunity to take part in these studies, many of which involve tests and treatments which we would not otherwise be able to offer. The practice is actively involved in numerous national studies which are organised by study teams at universities, charities and other research institutions.

Taking Part

Taking part in research

Banbury Cross Health Centre is involved in medical research, and from time to time, you may be approached to take part. Taking part in research is voluntary: you can freely accept or decline, and this will not affect the care that you receive in any way. Even if you agree to take part, you can still withdraw at any time, without having to provide justification. Withdrawing from a study will not affect the care we provide for you.

All research projects carried out at Banbury Cross Health Centre have been thoroughly checked and approved by the relevant health authorities and ethical committees, ensuring it is appropriate and safe to perform.

You will always receive clear information about what taking part in a research study would involve and will have the opportunity to ask questions and obtain further details about a study. All projects are fully compliant with all UK laws (incl. GDPR).

  • You may receive a text message or a letter in the post offering you the opportunity to take part in a study (the letter will include some information about the project).
  • Your doctor or nurse may also discuss research opportunities during your usual appointment.
  • You may also be approached by a member of the study team in the waiting area; be assured that this person and their activity will have been approved by the practice.

What you will be asked to do as part of the research will vary from study to study. The Patient Information Sheet for each project will detail what is expected of you. The study team is also there to answer all questions you may have.

Things you may want to know

  • Participation in research is entirely voluntary, and you have the right to say ‘No’. Nobody will put pressure on you to take part in research if you do not wish to. You do not have to give us a reason if you decide not to take part.
  • Your care and your relationship with your doctor or nurse will not be affected in any way if you decide not to take part in a research study.
  • You will always receive clear information about what taking part in a research study would involve.  The practice will usually provide you with a patient information sheet; then, if you agree to take part, the study team will explain the study to you in more detail, and you will have the opportunity to ask questions about it.
  • Nobody from outside this practice will be given your contact details or have access to your medical records without your prior consent. If you do agree to take part in a study, you will be asked to sign a consent form – this will clearly state which parts of your notes (if any) may be looked at for the purposes of the research.
  • You will not be asked to take part in a large number of studies.  Most researchers are very specific about the criteria that people need to meet in order to enter their study.  Usually this means that only a relatively small number of patients at the practice will be suitable for any one study.

Anonymous data sharing for research

This practice is also participating in two national database projects which collect anonymised electronic medical records collected from GP surgeries throughout the UK. Through the electronic clinical system we use to record medical notes, a completely anonymous (i.e. no identifiable patient details are shared at all) extract is taken which is used for medical research. This clinical data is then catalogued and provides continuous monitoring of infection and disease around the UK.

What if I don’t want to get involved in research?

We recognise that some people may not want to receive information about research studies by post or text message. If you do not want to be contacted about research studies that we may run at the practice in the future, please let us know. If you change your mind at a later date, you can still opt back in at any time.

To opt out of participating in any research studies visit the NHS Your Data Matters website to set your preferences

Current Research Studies

We are currently recruiting patients for the following studies. Select a project for a summary, eligibility criteria, and contact details.

Active Brains

To assess how well their website works. ‘Active Brains’ aims to help older adults look after their brain and body health. The aim is to help prevent problems with things like remembering, concentrating or reasoning (known as cognitive decline). The website will help older adults to make simple changes such as getting more active, playing brain training games and finding ways to eat more healthily.

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AMALFI

Comparing a single two-week screening period for AF with the Zio system to usual care in individuals with no history of AF and elevated risk of stroke, based on the CHA2DS2-VASc score.

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ATHENA

To determine the clinical and cost effectiveness of prophylactic low-dose amitriptyline for the prevention of post-herpetic neuralgia (PHN) in patients diagnosed with herpes zoster (HZ). (Shingles)

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Baby Fuss

To interview parents and carers of infants (12 months of age or younger) to explore their understanding of symptoms and their feeding decisions and help-seeking behaviour. A better understanding of parents and carers’ experiences and actions will inform future research on how healthcare professionals can best help parents and carers look after infants while avoiding unnecessary or excessive use of medications.

CatheterII

To determine whether the addition of a policy of prophylactic catheter washouts on a weekly basis to the current standard LTC care improves the outcome of cared for people living with LTC in the UK.

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CCP Next Gen

The aim is to determine the proportion of community patients with new-onset, non-specific musculoskeletal complaints who are anti-CCP antibody positive by identifying a cohort of individuals at high risk of developing inflammatory arthritis (IA), who may be appropriate for interventional research (including drug trials) aimed at preventing progression to IA.

COAT (Cellelitis Optimal Antibiotic Treatment)

Cellulitis is a deep infection of the skin and subcutaneous tissues, and most often occurs in the legs. It is a painful condition that is associated with inflammation and swelling of the site, and often systemic symptoms such as fever, headache, muscle aches, malaise, and fatigue. Patients report feeling unwell and that it has a significant impact on their mobility and ability to carry out their usual activities. NICE guidelines recommend oral flucloxacillin 500 to 1000 mg four times daily for 5 to 7 days as first-line treatment for most patients with cellulitis in the community, but most prescriptions are dispensed for a 7-day course.

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Com-CoV

The purpose of this study is to find out how well young people (aged 12 to 16 years) respond to two doses of COVID-19 vaccine. They want to find out if giving two doses of different vaccines produces as good an immune response as giving two doses of the same vaccine, in young people.

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CROCUS

Patients with urinary tract infection (UTI). The aim of this project is to evaluate the circumstances around a patient’s own behaviour and primary care management regarding UTI-derived E.coli septicaemia and to determine if there are variables that are significantly associated with this condition.

DaRe2THINK

A study to evaluate whether oral anticoagulants can prevent stroke, premature death and cognitive decline in a broader community of patients with atrial fibrillation using healthcare data for pragmatic research: A randomised controlled trial

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DURATION

Study aiming to find the shortest length of time we can give someone an antibiotic when they have a urinary tract infection (UTI) and still be able to treat that infection effectively

E.mbrace

The E.mbrace Study will assess the effectiveness and safety of an investigational vaccine versus a placebo – a vaccine that contains no active drug but which will look exactly like the investigational vaccine – in the prevention of a bloodstream infection in adults aged 60 or over who have had a urinary tract infection (UTI) in the past two years. The investigational vaccine or placebo will be given as a single injection.

EMBRACE

Assess the Efficacy, Safety And Immunogenicity of Vaccination With ExPECMV in the Prevention of Invasive Extraintestinal Pathogenic Escherichia coli Disease (IED) in Adults Aged 60 Years And Older with a History of Urinary Tract Infection in the Past 2 Years.

Gentle Years Yoga (GYY)

Study looking into whether Yoga can help to improve health and wellbeing in patients over 65 with multimorbidities, defined as when a person has two or more long-term health conditions.

Harmonie

Help further research on RSV infection (respiratory syncytial virus). If your baby is newborn to 12 months old, they may be eligible to participate in a study looking at how babies may be protected from serious illness due to RSV infection (respiratory syncytial virus). 

HipDyS

Evaluation of aid to diagnosis for congenital dysplasia of the hip in general practice: controlled randomised trial

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LTC Scale

Eligible patients are asked to complete the scale and five additional validated questionnaires which will measure how the perceive their quality and satisfaction with life; what additional support, if any, they receive to help with daily life.

NewKI

Cardiovascular disease is a major cause of morbidity and death in CKD. This study looks at prevalence, incidence and progression of CKD in the UK and alternative renal biomarkers may have greater accuracy for cardiovascular risk stratification but their predictive role as assessed in prospective studies has not been established.

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OPTIMISE2

Looking at deprescribing antihypertensive medication in the over 75s.

OxVALVE

Two aims: firstly, to identify people with Valvular Heart Disease and hence to establish its incidence within the population. Secondly, by further investigation we hope to develop improved treatment strategies for Valvular Heart Disease.

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PAM

A study evaluating a new text message/ smartphone app intervention aiming to support medication adherence to people prescribed treatment for hypertension.

PANORAMIC

PANORAMIC aims to determine the effectiveness of selected antiviral agents in preventing hospitalisation and/or death in higher-risk patients with a confirmed positive SARS-CoV-2 PCR test result.

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PATHOR

To evaluate the effectiveness of an online hub of newly developed resources which aim to improve knowledge of and de-stigmatise PMI (perinatal mental illness) for prospective/new parents, healthcare professionals and employers.

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PRINCIPLE

The PRINCIPLE trial aims to find treatments that reduce hospital admission and improve symptoms for people with COVID-19.

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PROMDEP

The study will look at whether giving personal feedback to people being treated for depression might help them get better more quickly. This will be done by using patient reported outcome measures ('PROMs') which involve patients completing questionnaires to record their symptoms of depression and feeding back these results to the practitioners looking after them.

QUAL-HF

This study aims to find out what people think of a potential new pathway to identify patients with heart failure.

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RAPTOR

A research study to compare how accurate different tests are at detecting past or current coronavirus (COVID-19) infection.

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RCGP serology surveillance

To provide information on background population immunity to Covid-19. This is important in order to detect the number of infections within the population and to help inform public health surveillance and planning.

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SAFER-AF

A programme of research investigating screening to detect atrial fibrillation, a heart condition responsible for one in ten strokes

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STATIC

To compare the safety and effectiveness of continuing existing 5-ASA medication versus stopping it in patients with Chron’s disease in remission.

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STREAM

Nutrition in older patients.

SuMMiT-D

Support through mobile messaging & digital health technology for diabetes.

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TAILOR

An observational study on preschool wheeze to help predict future wheezing exacerbations and guide treatment more efficiently.

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Treat to target T2T Gout

A study to determine the clinical and cost-effectiveness of treat-to-target urate lowering therapy in people with recurrent gout flares compared to usual care.

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TOUCAN

The TOUCAN study is testing new devices that, hopefully, will quickly tell a GP whether a patient has a urinary tract infection.

VASP

Development of a Live Attenuated Vaccine against Salmonella Paratyphi A. VASP aims to find out if a weakened form of Salmonella Paratyphi A bacteria can act as a vaccine to protect individuals without causing disease.

Virus Watch

To work out why Covid-19 is affecting some communities more than others by learning from people in every community in the UK. We will be looking into access, and effectiveness of, Covid-19 vaccines.

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